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Predicting the fate of stem cells: New method decodes cell movements, accurately predicts how cells will divide
Researchers have discovered a new method for predicting -- with up to 99 percent accuracy -- the fate of stem cells. Using advanced computer vision technology to detect subtle cell movements that are impossible to discern with the human eye, scientists can successfully forecast how a stem cell will split and what key characteristics the daughter cells will exhibit.
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Another serious eye disease, uveitis, linked to smoking
Smoking is already a known risk factor for age-related macular degeneration, cataract and thyroid eye disease. Now, the first study to specifically examine the impact of smoking on uveitis-inflammation of the eye's middle layer of tissue-indicates that tobacco smoke likely plays a role in this serious eye disease, as well. In the United States about 10 percent of blindness is caused by uveitis.
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Atmospheric nanoparticles impact health, weather professor says
Nanoparticles are atmospheric materials so small that they can't be seen with the naked eye, but they can very visibly affect both weather patterns and human health all over the world -- and not in a good way, according to a new study.
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Newer cornea transplant surgery shows short- and long-term promise
One year post-surgery, patients who underwent Descemet's stripping automated endothelial keratoplasty (DSAEK) experienced greater cell loss overall compared to those who underwent penetrating keratoplasty (PKP), according to a new analysis of data. However, the study showed that cell loss in DSAEK patients plateaued more quickly than in those who underwent PKP.
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Mechanism for Frank-Ter Haar syndrome discovered
Scientists have discovered that TKS4, a protein implicated in cancer metastasis, also plays a significant role in Frank-Ter Haar syndrome, a rare fatal disorder.
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More evidence on benefits of high blood pressure drugs in diabetic eye disease
Scientists in Massachusetts are reporting new evidence that certain high blood pressure drugs may be useful in preventing and treating diabetic retinopathy, the leading cause of vision loss in people with diabetes. The study, the largest to date on proteins in the retina, could lead to new ways to prevent or treat the sight-threatening disease, they say.
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New strategy develops two prototype drugs against cancer, retinal diseases
A comprehensive drug development strategy that starts with extensive screening of potential targeting peptides to identify prototype small-molecule drugs has produced two that target the EGFR and VEGFR pathways in novel ways.
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Stem cells restore sight in mouse model of retinitis pigmentosa
Scientists have successfully used mouse embryonic stem cells to replace diseased retinal cells and restore sight in a mouse model of retinitis pigmentosa. This strategy could potentially become a new treatment for retinitis pigmentosa, a leading cause of blindness that affects approximately one in 3,000 to 4,000 people, or 1.5 million people worldwide.
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Engineer creates unique software that predicts stem cell fate
A completely novel approach to analyzing time-lapse images of live stem cell behaviors has yielded a tool for successfully predicting outcomes of stem and progenitor cells. It will allow scientists to search for mechanisms that control stem cell specialization, the main obstacle in advancing the use of stem cell therapy for treatment of disease.
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In schizophrenia and bipolar disorder, life is not black and white
Schizophrenia and bipolar disorder affect 10s of millions of individuals around the world. These disorders have a typical onset in the early 20s and in most cases have a chronic or recurring course. Neither disorder has an objective biological marker than can be used to make diagnoses or to guide treatment.
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Midday nap markedly boosts the brain's learning capacity
If you see a student dozing in the library or a co-worker catching 40 winks in her cubicle, don't roll your eyes. New research shows that an hour's nap can dramatically boost and restore your brain power. Indeed, the findings suggest that a biphasic sleep schedule not only refreshes the mind, but can make you smarter.
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New evidence that green tea may help fight glaucoma and other eye diseases
Scientists have confirmed that the healthful substances found in green tea -- renowned for their powerful antioxidant and disease-fighting properties -- do penetrate into tissues of the eye. Their new report, the first documenting how the lens, retina, and other eye tissues absorb these substances, raises the possibility that green tea may protect against glaucoma and other common eye diseases.
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Untreated poor vision in elderly linked to dementia study shows
Elderly people with visual disorders that are left untreated are significantly more likely to develop dementia, according to new research. Early treatment of visual problems may delay the development of dementia, but because many elderly lack adequate vision coverage, they are not seeking care. This study may draw a picture of poor vision as a possible contributor to the onset of dementia, rather than as a symptom.
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Critical step in fly vision discovered; offers clues to treating retinal degeneration in humans
Research by sensory biologists studying fruit flies has revealed a critical step in fly vision. Humans with problems in this same step suffer retinal dystrophies, which manifest as visual defects ranging from mild visual impairments to complete blindness. The article paves the way for using the fruit fly to screen for therapies to treat human retinal degeneration.
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Autism's earliest symptoms not evident in children under 6 months, study finds
A study of the development of autism in infants, comparing the behavior of the siblings of children diagnosed with autism to that of babies developing normally, has found that the nascent symptoms of the condition.
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Botulinum toxin injection may help prevent some types of migraine pain
A preliminary study suggests the same type of botulinum injection used for cosmetic purposes may be associated with reduced frequency of migraine headaches that are described as crushing, vicelike or eye-popping (ocular), but not pain that is experienced as a buildup of pressure inside the head, according to a new article.
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Chickens 'one-up' humans in ability to see color
Researchers have peered deep into the eye of the chicken and found a masterpiece of biological design. Scientists mapped five types of light receptors in the chicken's eye. They discovered the receptors were laid out in interwoven mosaics that maximized the chicken's ability to see many colors in any given part of the retina, the light-sensing structure at the back of the eye.
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Autism: Oxytocin improves social behavior of patients, study finds
Autism is a disease characterized by difficulties in communicating effectively with other people and developing social relationships. New research in France shows that the inhalation of oxytocin, a hormone known to promote mother-infant bonds and social relationships, significantly improved the abilities of autistic patients to interact with other individuals.
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Scientists discover molecular pathway for organ tissue regeneration and repair
Scientists have discovered a molecular pathway that works through the immune system to regenerate damaged kidney tissues and may lead to new therapies for repairing injury in other organs. The study may have significant medical ramifications as currently there are no effective treatments for acute kidney injury -- a growing problem in hospitals and clinics.
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Glaucoma medications may be associated with reduced risk of death over 4-year period
Glaucoma patients who take medication for the condition appear to have a reduced likelihood of death, according to a new study.
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